The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases

The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases

Higher prevalence of neurodegenerative diseases is strictly connected with progressive aging of the world population. Interestingly, a broad range of age-related, neurodegenerative diseases is characterized by a common pathological mechanism—accumulation of misfolded and unfolded proteins...

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Bibliographic Details
Main Authors:	Wioletta Rozpędek-Kamińska, Natalia Siwecka, Adam Wawrzynkiewicz, Radosław Wojtczak, Dariusz Pytel, J. Alan Diehl, Ireneusz Majsterek
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Series:	International Journal of Molecular Sciences
Subjects:	neurodegenerative diseases neurodegeneration alzheimer’s disease parkinson’s disease perk endoplasmic reticulum stress unfolded protein response apoptosis perk inhibitors
Online Access:	https://www.mdpi.com/1422-0067/21/6/2108

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