Severe infective endocarditis with systemic embolism due to community associated methicillin-resistant Staphylococcus aureus ST630

• Main Authors: Beiwen Zheng, Saiping Jiang, Zemin Xu, Yonghong Xiao, Lanjuan Li
• Format: Article
• Language: English
• Published: Elsevier 2015-01-01
• Series: Brazilian Journal of Infectious Diseases
• Online Access: http://www.sciencedirect.com/science/article/pii/S1413867014001718

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly causing infective endocarditis over the past decade. Here we report a healthy man who developed a severe acute infective endocarditis with systemic embolism caused by CA-MRSA. The strain was recovered from repeated blood cultures and was characterized using molecular detection and genotyping. The S. aureus isolate was typed as ST630 SCCmecV with spa-type t4549, agrI/IV and was PVL-negative. This is the only case report, to our knowledge, of CA-MRSA infective endocarditis in China. This case highlights the emergence and geographical spread of life-threatening CA-MRSA infection within China. Keywords: Community-acquired MRSA, Infective endocarditis, ST 630, Surgical therapy