Anti Cariogenic Effect of Terminalia Chebula
Background: Terminalia chebula is one of the traditional medicines used in the treatment of many diseases and possesses a wide variety of therapeutic activities. The aim of this study was to determine the antimicrobial properties of Terminalia chebula against oral pathogens related to caries. M...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2014-08-01
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Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/4765/9844_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(P).pdf |
Summary: | Background: Terminalia chebula is one of the traditional
medicines used in the treatment of many diseases and
possesses a wide variety of therapeutic activities. The aim
of this study was to determine the antimicrobial properties of
Terminalia chebula against oral pathogens related to caries.
Materials and Methods: In this study, Antimicrobial activity was
tested using Kirby bouer method by streaking. Total phenol and
total flavonoid content were analysed. Twenty high caries risk
patients were subjected to rinse aqueous extract of Terminalia
chebula. Salivary samples were collected for pH and microbial
screening. Oral pathogens were identified by qualitative
biochemical analysis.
Results: The total phenol content of extract was found to be
21.33 ±1.633 (mean ± SD) and total flavonoids was found to be
23.17 ± 2.317 (mean ± SD). There was a gradual increase in pH
till 45mts post-rinse when compared to pre-rinse was observed.
Antimicrobial effect of Terminalia Chebula aganist microbes
showed that there was a significant reduction between the prerinse and post-rinse samples.
Conclusion: These promising findings suggested the presence
of antimicrobial activity of Terminalia Chebula against oral
pathogens and proven to be an effective alternate antimicrobial
agent. |
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ISSN: | 2249-782X 0973-709X |