Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella
Neopterin concentrations reflect the activation of the cellular immune system. Neopterin is released by macrophages stimulated by interferon-γ (IFN-γ), which is produced by activated T lymphocytes. Raised neopterin concentrations in body fluids are found in various disorders, e.g. viral infections (...
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De Gruyter
2009-02-01
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Online Access: | https://doi.org/10.1515/pteridines.2009.20.1.119 |
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doaj-df10f04857be4db1a24681110b1678312021-09-05T14:00:03ZengDe GruyterPteridines0933-48072195-47202009-02-0120111912310.1515/pteridines.2009.20.1.119Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or SalmonellaKozlowska-Murawska Jolanta0Obuchowicz Anna1Katedra i Oddzial Kliniczny Pediatrii, ul. Batorego 15, 41-902 Bytom, Polska, Krasna 60/3, 26-220 Staporkow, PolskaDepartment of Pediatrics, ul. Batorego 15, 41-902 Bytom, PolandNeopterin concentrations reflect the activation of the cellular immune system. Neopterin is released by macrophages stimulated by interferon-γ (IFN-γ), which is produced by activated T lymphocytes. Raised neopterin concentrations in body fluids are found in various disorders, e.g. viral infections (AIDS, cytomegalovirus, hepatitis), intracellular bacteria infections (Mycobacteruim tuberculosis, Mycobacterium leprae), autoimmune disorders and malignancy. Neopterin concentrations are low or not significantly increased in bacterial infections, with exception of infections with intracellular bacteria. The aim of this study was to evaluate the usefulness of neopterin in the differential diagnosis of viral (Rotavirus) and bacterial (Salmonella) origin of diarrhoea.https://doi.org/10.1515/pteridines.2009.20.1.119neopterinrotavirussalmonellaviral infectionchildren |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kozlowska-Murawska Jolanta Obuchowicz Anna |
spellingShingle |
Kozlowska-Murawska Jolanta Obuchowicz Anna Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella Pteridines neopterin rotavirus salmonella viral infection children |
author_facet |
Kozlowska-Murawska Jolanta Obuchowicz Anna |
author_sort |
Kozlowska-Murawska Jolanta |
title |
Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella |
title_short |
Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella |
title_full |
Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella |
title_fullStr |
Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella |
title_full_unstemmed |
Neopterin Concentration in Serum and Chosen Markers of Inflammatory Process in Children with Acute Diarrhea Caused by Rotavirus or Salmonella |
title_sort |
neopterin concentration in serum and chosen markers of inflammatory process in children with acute diarrhea caused by rotavirus or salmonella |
publisher |
De Gruyter |
series |
Pteridines |
issn |
0933-4807 2195-4720 |
publishDate |
2009-02-01 |
description |
Neopterin concentrations reflect the activation of the cellular immune system. Neopterin is released by macrophages stimulated by interferon-γ (IFN-γ), which is produced by activated T lymphocytes. Raised neopterin concentrations in body fluids are found in various disorders, e.g. viral infections (AIDS, cytomegalovirus, hepatitis), intracellular bacteria infections (Mycobacteruim tuberculosis, Mycobacterium leprae), autoimmune disorders and malignancy. Neopterin concentrations are low or not significantly increased in bacterial infections, with exception of infections with intracellular bacteria. The aim of this study was to evaluate the usefulness of neopterin in the differential diagnosis of viral (Rotavirus) and bacterial (Salmonella) origin of diarrhoea. |
topic |
neopterin rotavirus salmonella viral infection children |
url |
https://doi.org/10.1515/pteridines.2009.20.1.119 |
work_keys_str_mv |
AT kozlowskamurawskajolanta neopterinconcentrationinserumandchosenmarkersofinflammatoryprocessinchildrenwithacutediarrheacausedbyrotavirusorsalmonella AT obuchowiczanna neopterinconcentrationinserumandchosenmarkersofinflammatoryprocessinchildrenwithacutediarrheacausedbyrotavirusorsalmonella |
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