TRPV4 is the temperature-sensitive ion channel of human sperm

TRPV4 is the temperature-sensitive ion channel of human sperm

Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium. Previous studies unraveled three essential ion channels that regulate these parameters: (1) the Ca2+ channel...

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Bibliographic Details
Main Authors: Nadine Mundt, Marc Spehr, Polina V Lishko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
TRPV4
ion channel
sperm cell
hyperactivation
CatSper
thermosensitivity
Online Access:https://elifesciences.org/articles/35853

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