Ferroptosis Mechanisms Involved in Neurodegenerative Diseases

Ferroptosis Mechanisms Involved in Neurodegenerative Diseases

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential as a redox metal in several physiological functions. The brain is one of the organs known to be affected by...

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Bibliographic Details
Main Authors: Cadiele Oliana Reichert, Fábio Alessandro de Freitas, Juliana Sampaio-Silva, Leonardo Rokita-Rosa, Priscila de Lima Barros, Debora Levy, Sérgio Paulo Bydlowski
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
ferroptosis
cell death
iron metabolism
neurodegenerative diseases
glutathione peroxidase 4
GSH
Online Access:https://www.mdpi.com/1422-0067/21/22/8765

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