Metal-responsive promoter DNA compaction by the ferric uptake regulator
The Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2016-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12593 |
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doaj-df1a4b051ef64998b7f2d859a4491d542021-05-11T10:43:04ZengNature Publishing GroupNature Communications2041-17232016-08-017111310.1038/ncomms12593Metal-responsive promoter DNA compaction by the ferric uptake regulatorDavide Roncarati0Simone Pelliciari1Nicola Doniselli2Stefano Maggi3Andrea Vannini4Luca Valzania5Luca Mazzei6Barbara Zambelli7Claudio Rivetti8Alberto Danielli9Department of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Life Sciences, University of ParmaDepartment of Life Sciences, University of ParmaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Life Sciences, University of ParmaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaThe Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex.https://doi.org/10.1038/ncomms12593 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli |
| spellingShingle |
Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli Metal-responsive promoter DNA compaction by the ferric uptake regulator Nature Communications |
| author_facet |
Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli |
| author_sort |
Davide Roncarati |
| title |
Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_short |
Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_full |
Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_fullStr |
Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_full_unstemmed |
Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_sort |
metal-responsive promoter dna compaction by the ferric uptake regulator |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-08-01 |
| description |
The Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex. |
| url |
https://doi.org/10.1038/ncomms12593 |
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AT davideroncarati metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT simonepelliciari metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT nicoladoniselli metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT stefanomaggi metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT andreavannini metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT lucavalzania metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT lucamazzei metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT barbarazambelli metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT claudiorivetti metalresponsivepromoterdnacompactionbytheferricuptakeregulator AT albertodanielli metalresponsivepromoterdnacompactionbytheferricuptakeregulator |
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