Methodologies and Challenges for CRISPR/Cas9 Mediated Genome Editing of the Mammalian Brain
Neurons and glia are highly polarized cells with extensive subcellular structures extending over large distances from their cell bodies. Previous research has revealed elaborate protein signaling complexes localized within intracellular compartments. Thus, exploring the function and the localization...
Main Authors: | Hirofumi Nishizono, Ryohei Yasuda, Tal Laviv |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
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Series: | Frontiers in Genome Editing |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgeed.2020.602970/full |
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