| Summary: | Abstract Background Posterior fossa brain tumours are one of the most devastating forms of human illnesses which are more common in children. Brainstem compression, herniation and death are the risks with tumours in this critical location. Objective To evaluate our results, complications and outcome of posterior fossa tumour surgery in Benha University Hospital. Patients and methods A prospective study including 44 patients with posterior fossa tumours were performed at the Neurosurgery Department in Benha University Hospital between the period of March 2015 and October 2018. In each case, diagnosis was made clinically and confirmed radiologically and histo-pathologically. Results Out of 44 patients, 28 (63.6%) patients were males and 16 (36.4%) were females. The mean age was 17.5 + 14.2 years (ranged 2–30 years). This study showed that excellent surgical outcome was observed in 12 cases (27.3%), good in 22 cases (50%) while poor outcome was observed in 10 cases (22.7%). The best outcome is astrocytoma then ependymoma while the worst outcome is metastatic then medulloblastoma which is statistically insignificant. Conclusion The surgical treatment of posterior fossa tumours still represents a challenge for neurosurgeons. Our Benha experience shows the accepted results, complications and surgical outcome in relation to previous clinical studies. Trial registration IRB#3747. Registered 18 September 2018.
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