| Summary: | The aim of this clinical study was to update the available data in the literature regarding the transfer accuracy (trueness/precision) of four current intraoral scanners (IOS) equipped with the latest software versions and to compare these data with conventional impressions (CVI). A metallic reference aid served as a reference dataset. Four digital impressions (Trios3Cart, Trios3Pod, Trios4Pod, and Primescan) and one CVI were investigated in five patients. Scan data were analyzed using three-dimensional analysis software and conventional models using a coordinate measurement machine. The transfer accuracy between the reference aid and the impression methods were compared. Differences with <i>p</i> < 0.05 were considered to be statistically significant. Overall, mean ± standard deviation (SD) transfer accuracy ranged from 24.6 ± 17.7 µm (CVI) to 204.5 ± 182.1 µm (Trios3Pod). The Primescan yielded the lowest deviation for digital impressions (33.8 ± 31.5 µm), followed by Trios4Pod (65.2 ± 52.9 µm), Trios3Cart (84.7 ± 120.3 µm), and Trios3Pod. Within the limitations of this study, current IOS equipped with the latest software versions demonstrated less deviation for short-span distances compared with the conventional impression technique. However, for long-span distances, the conventional impression technique provided the lowest deviation. Overall, currently available IOS systems demonstrated improvement regarding transfer accuracy of full-arch scans in patients.
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