Mutation Analysis of the BRCA1 and BRCA2 Genes in the Belgian Patient Population and Identification of a Belgian Founder Mutation BRCA1 IVS5+3A>G
Since the identification of the BRCA1 and BRCA2 genes, several hundred different germline mutations in both genes have been reported. Recurrent mutations are rare and mainly due to founder effects. As the mutational spectrum of the BRCA1 and BRCA2 genes in the Belgian patient population is largely u...
Main Authors: | Kathleen Claes, Eva Machackova, Michel De Vos, Bruce Poppe, Anne De Paepe, Ludwine Messiaen |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1999-01-01
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Series: | Disease Markers |
Online Access: | http://dx.doi.org/10.1155/1999/241046 |
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