Simultaneous triple therapy for the treatment of status epilepticus

Simultaneous triple therapy for the treatment of status epilepticus

Early maladaptive internalization of synaptic GABAA receptors (GABAAR) and externalization of NMDA receptors (NMDAR) may explain the time-dependent loss of potency of standard anti-epileptic drugs (AED) in refractory status epilepticus (SE). We hypothesized that correcting the effects of changes in...

Full description

Bibliographic Details
Main Authors: Jerome Niquet, Roger Baldwin, Keith Norman, Lucie Suchomelova, Lucille Lumley, Claude G. Wasterlain
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Neurobiology of Disease
Subjects:
Refractory status epilepticus
Cholinergic seizures
Midazolam
Ketamine
Valproate
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301006

Similar Items

Similar Items