Design, Synthesis, and Anticancer Evaluation of Novel Indole Derivatives of Ursolic Acid as Potential Topoisomerase II Inhibitors

In this study, a series of new indole derivatives of ursolic acid bearing different <i>N</i>-(aminoalkyl)carboxamide side chains were designed, synthesized, and evaluated for their in vitro cytotoxic activities against two human hepatocarcinoma cell lines (SMMC-7721 and HepG2) and normal...

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Bibliographic Details
Main Authors: A-Liang Li, Yun Hao, Wen-Yan Wang, Qing-Song Liu, Yue Sun, Wen Gu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/8/2876