Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering
<span>Diopside exhibits favorable potential for bone repair on account of the good mechanical performance, bioactivity and biocompatibility. In this paper, diopside scaffolds with high pore interconnectivity were successfully fabricated by laser three-dimensional (3D) printing. The microstruct...
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Kaunas University of Technology
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doaj-df52f55df4984f35bfcc46cb5496dee42020-11-25T01:05:14ZengKaunas University of TechnologyMedžiagotyra1392-13202029-72892015-11-0121459059410.5755/j01.ms.21.4.98456625Analysis of 3D Printed Diopside Scaffolds Properties for Tissue EngineeringTingting LIUYouwen DENGChengde GAOPei FENGCijun SHUAIShuping PENG<span>Diopside exhibits favorable potential for bone repair on account of the good mechanical performance, bioactivity and biocompatibility. In this paper, diopside scaffolds with high pore interconnectivity were successfully fabricated by laser three-dimensional (3D) printing. The microstructure and mechanical performance of the diopside scaffolds were studied. The experimental analysis indicated that diopside particles gradually fused together until a dense structure was built with an energy density increasing in the range between 2.4 and 4.8 J·mm<sup>-2</sup>. Meanwhile, compressive strength and fracture toughness increased gradually from 5.96 ± 0.88 MPa to 10.87 ± 0.55 MPa. However, mechanical properties decreased due to the appearance of voids when energy density were 5.4 and 6 J·mm<sup>-2</sup>. Simulated body fluid (SBF) tests showed that apatite crystals formed on the diopside scaffolds surface, and the apatite crystals increased with soaking time. Cell culture tests indicated the scaffolds supported the adhesion and growth of MG-63 cells. The study suggested that diopside scaffolds fabricated by laser 3D printing are promising candidates for bone tissue engineering.</span><p>DOI: <a href="http://dx.doi.org/10.5755/j01.ms.21.4.9845">http://dx.doi.org/10.5755/j01.ms.21.4.9845</a></p>http://matsc.ktu.lt/index.php/MatSc/article/view/9845diopside, scaffold, laser 3D printing, bone tissue engineering |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tingting LIU Youwen DENG Chengde GAO Pei FENG Cijun SHUAI Shuping PENG |
spellingShingle |
Tingting LIU Youwen DENG Chengde GAO Pei FENG Cijun SHUAI Shuping PENG Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering Medžiagotyra diopside, scaffold, laser 3D printing, bone tissue engineering |
author_facet |
Tingting LIU Youwen DENG Chengde GAO Pei FENG Cijun SHUAI Shuping PENG |
author_sort |
Tingting LIU |
title |
Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering |
title_short |
Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering |
title_full |
Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering |
title_fullStr |
Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering |
title_full_unstemmed |
Analysis of 3D Printed Diopside Scaffolds Properties for Tissue Engineering |
title_sort |
analysis of 3d printed diopside scaffolds properties for tissue engineering |
publisher |
Kaunas University of Technology |
series |
Medžiagotyra |
issn |
1392-1320 2029-7289 |
publishDate |
2015-11-01 |
description |
<span>Diopside exhibits favorable potential for bone repair on account of the good mechanical performance, bioactivity and biocompatibility. In this paper, diopside scaffolds with high pore interconnectivity were successfully fabricated by laser three-dimensional (3D) printing. The microstructure and mechanical performance of the diopside scaffolds were studied. The experimental analysis indicated that diopside particles gradually fused together until a dense structure was built with an energy density increasing in the range between 2.4 and 4.8 J·mm<sup>-2</sup>. Meanwhile, compressive strength and fracture toughness increased gradually from 5.96 ± 0.88 MPa to 10.87 ± 0.55 MPa. However, mechanical properties decreased due to the appearance of voids when energy density were 5.4 and 6 J·mm<sup>-2</sup>. Simulated body fluid (SBF) tests showed that apatite crystals formed on the diopside scaffolds surface, and the apatite crystals increased with soaking time. Cell culture tests indicated the scaffolds supported the adhesion and growth of MG-63 cells. The study suggested that diopside scaffolds fabricated by laser 3D printing are promising candidates for bone tissue engineering.</span><p>DOI: <a href="http://dx.doi.org/10.5755/j01.ms.21.4.9845">http://dx.doi.org/10.5755/j01.ms.21.4.9845</a></p> |
topic |
diopside, scaffold, laser 3D printing, bone tissue engineering |
url |
http://matsc.ktu.lt/index.php/MatSc/article/view/9845 |
work_keys_str_mv |
AT tingtingliu analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering AT youwendeng analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering AT chengdegao analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering AT peifeng analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering AT cijunshuai analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering AT shupingpeng analysisof3dprinteddiopsidescaffoldspropertiesfortissueengineering |
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