Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts

Rapid Endothelialization of Off-the-Shelf Small Diameter Silk Vascular Grafts

Synthetic vascular grafts for small diameter revascularization are lacking. Clinically available conduits expanded polytetrafluorethylene and Dacron fail acutely due to thrombosis and in the longer term from neointimal hyperplasia. We report the bioengineering of a cell-free, silk-based vascular gra...

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Bibliographic Details
Main Authors: Elysse C. Filipe, MSc, Miguel Santos, MSc, Juichien Hung, MSc, Bob S.L. Lee, MSc, Nianji Yang, MPhil, Alex H.P. Chan, BSc, Martin K.C. Ng, MD, PhD, Jelena Rnjak-Kovacina, PhD, Steven G. Wise, PhD
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:JACC: Basic to Translational Science
Subjects:
rat aortic interposition
silk
small diameter
vascular graft
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X18300020

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