Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier

Summary Although tight junctions (TJ) have been extensively studied in simple epithelial cells, it is still unknown whether their organization is coupled to cell differentiation in stratified epithelia. We studied the expression of TJ in RCE1(5T5) cells, an in vitro model which mimics the sequential...

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Bibliographic Details
Main Authors: María Teresa Ortiz-Melo, Erika Sánchez-Guzmán, Arturo González-Robles, Jesús Valdés, Eber Gómez-Flores, Federico Castro-Muñozledo
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/2/132