Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance

The antibiotic resistance crisis calls for new ways of restricting the ability of bacteria to evolve resistance. Here, Lukačišinová et al. perform highly controlled evolution experiments in E. coli strains to identify genetic perturbations that strongly limit the evolution of antibiotic resistance t...

Full description

Bibliographic Details
Main Authors: Marta Lukačišinová, Booshini Fernando, Tobias Bollenbach
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16932-z