Grafting chitosan with polyethylenimine in an ionic liquid for efficient gene delivery.
Modifying chitosan (CS) with polyethylenimine (PEI) grafts is an effective way to improve its gene transfection performance. However, it is still a challenge to conduct the grafting with fine control and high efficiency, particularly for the modification of water-insoluble CS. Herein, a novel method...
Main Authors: | Huiying Chen, Shaohui Cui, Yinan Zhao, Chuanmin Zhang, Shubiao Zhang, Xiaojun Peng |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4395340?pdf=render |
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