Intraoperative Confocal Laser Endomicroscopy Ex Vivo Examination of Tissue Microstructure During Fluorescence-Guided Brain Tumor Surgery

Intraoperative Confocal Laser Endomicroscopy Ex Vivo Examination of Tissue Microstructure During Fluorescence-Guided Brain Tumor Surgery

BackgroundNoninvasive intraoperative optical biopsy that provides real-time imaging of histoarchitectural (cell resolution) features of brain tumors, especially at the margin of invasive tumors, would be of great value. To assess clinical-grade confocal laser endomicroscopy (CLE) and to prepare for...

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Bibliographic Details
Main Authors: Evgenii Belykh, Xiaochun Zhao, Brandon Ngo, Dara S. Farhadi, Vadim A. Byvaltsev, Jennifer M. Eschbacher, Peter Nakaji, Mark C. Preul
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
brain histology
brain tumor
confocal laser endomicroscopy
fluorescein sodium
fluorescence
frozen section
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.599250/full

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