In vivo detection of extrapancreatic insulin gene expression in diabetic mice by bioluminescence imaging.

Extrapancreatic tissues such as liver may serve as potential sources of tissue for generating insulin-producing cells. The dynamics of insulin gene promoter activity in extrapancreatic tissues may be monitored in vivo by bioluminescence-imaging (BLI) of transgenic mice Tg(RIP-luc) expressing the fir...

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Bibliographic Details
Main Authors: Xiaojuan Chen, Courtney S Larson, Jason West, Xiaomin Zhang, Dixon B Kaufman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2827564?pdf=render