In vivo detection of extrapancreatic insulin gene expression in diabetic mice by bioluminescence imaging.
Extrapancreatic tissues such as liver may serve as potential sources of tissue for generating insulin-producing cells. The dynamics of insulin gene promoter activity in extrapancreatic tissues may be monitored in vivo by bioluminescence-imaging (BLI) of transgenic mice Tg(RIP-luc) expressing the fir...
Main Authors: | Xiaojuan Chen, Courtney S Larson, Jason West, Xiaomin Zhang, Dixon B Kaufman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2827564?pdf=render |
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