Inhibitory Effect of Trimidox on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 264.7 Macrophages
We examined the effect of trimidox (3,4,5-trihydroxybenzamidoxime) on the production of nitric oxide (NO) by lipopolysaccharide (LPS) in mouse RAW 264.7 macrophages. Trimidox (50 – 300 µM) concentration-dependently inhibited NO production by LPS (0.01, 0.1, or 1 µg/ml) after incubation for 24 h. LPS...
Main Authors: | Syu-ichi Kanno, Mai Kakuta, Yasue Kitajima, Yuu Osanai, Kaori Kurauchi, Takaharu Ohtake, Mayuko Ujibe, Kouji Uwai, Mituhiro Takeshita, Masaaki Ishikawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2007-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319342549 |
Similar Items
-
Trimidox-Induced Apoptosis Is Mediated Through Induction of p53 in NALM-6 Cells
by: Syu-ichi Kanno, et al.
Published: (2008-01-01) -
Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox
by: Inayat Mohammed S, et al.
Published: (2010-08-01) -
Inductive Effect of Palmatine on Apoptosis in RAW 264.7 Cells
by: Shintaro Ishikawa, et al.
Published: (2016-01-01) -
The uptake of tocopherols by RAW 264.7 macrophages
by: Papas Andreas M, et al.
Published: (2002-10-01) -
Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages
by: Nan Liu, et al.
Published: (2014-06-01)