Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin
<p>Abstract</p> <p>Background</p> <p>Influenza A virus non-structural protein 1 (NS1) is a virulence factor, which is targeted into the cell cytoplasm, nucleus and nucleolus. NS1 is a multi-functional protein that inhibits host cell pre-mRNA processing and counteracts h...
Main Authors: | Melén Krister, Tynell Janne, Fagerlund Riku, Roussel Pascal, Hernandez-Verdun Danièle, Julkunen Ilkka |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | Virology Journal |
Subjects: | |
Online Access: | http://www.virologyj.com/content/9/1/167 |
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