Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer

Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer

Ovarian cancer (OC) is sensitive to upfront chemotherapy, which is likely attributable to defects in DNA damage repair (DDR). Unfortunately, patients relapse and the evolution of DDR competency are poorly described. We examined the expression of proposed effectors in homologous recombination (HR: RA...

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Bibliographic Details
Main Authors: Paul Kubelac, Catherine Genestie, Aurelie Auguste, Soizick Mesnage, Audrey Le Formal, Patricia Pautier, Sebastien Gouy, Philippe Morice, Enrica Bentivegna, Amandine Maulard, Julien Adam, Patriciu Achimas-Cadariu, Alexandra Leary
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
ovarian cancer
dna damage repair
temporal heterogeneity
survival
Online Access:https://www.mdpi.com/2072-6694/12/3/707

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