Investigating epithelial‐mesenchymal heterogeneity of tumors and circulating tumor cells with transcriptomic analysis and biophysical modeling
Abstract Cellular heterogeneity along the epithelial‐mesenchymal plasticity (EMP) spectrum is a paramount feature observed in tumors and circulating tumor cells (CTCs). High‐throughput techniques now offer unprecedented details on this variability at a single‐cell resolution. Yet, there is no curren...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-06-01
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Series: | Computational and Systems Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/cso2.1015 |