Investigating epithelial‐mesenchymal heterogeneity of tumors and circulating tumor cells with transcriptomic analysis and biophysical modeling

Abstract Cellular heterogeneity along the epithelial‐mesenchymal plasticity (EMP) spectrum is a paramount feature observed in tumors and circulating tumor cells (CTCs). High‐throughput techniques now offer unprecedented details on this variability at a single‐cell resolution. Yet, there is no curren...

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Bibliographic Details
Main Authors: Federico Bocci, Susmita Mandal, Tanishq Tejaswi, Mohit Kumar Jolly
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Computational and Systems Oncology
Subjects:
Online Access:https://doi.org/10.1002/cso2.1015