Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

Background: Plasma insulin levels are predominantly the product of the morphological mass of insulin producing beta cells in the pancreatic islets of Langerhans and the functional status of each of these beta cells. Thus, deficiency in either beta cell mass or function, or both, can lead to insuffic...

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Bibliographic Details
Main Authors: Chunguang Chen, Christian M. Cohrs, Julia Stertmann, Robert Bozsak, Stephan Speier
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817302259

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