Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development.

Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development.

Streptococcus iniae is a significant pathogen in finfish aquaculture, though knowledge of virulence determinants is lacking. Through pyrosequencing of the S. iniae genome we have identified two gene homologues to classical surface-anchored streptococcal virulence factors: M-like protein (simA) and C...

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Bibliographic Details
Main Authors: Jeffrey B Locke, Ramy K Aziz, Mike R Vicknair, Victor Nizet, John T Buchanan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2483786?pdf=render

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