Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef

The role of HIV-specific CD8 T cell activity in the course of HIV infection and the way it affects the virus that resides in the latent reservoir resting memory cells is debated. The PBMC of HIV-infected patients contain HIV-specific CD8 T cells and their potential targets, CD4 T cells latently infe...

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Bibliographic Details
Main Authors: Ziv Sevilya, Ehud Chorin, Orit Gal-Garber, Einat Zelinger, Dan Turner, Boaz Avidor, Gideon Berke, David Hassin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
HIV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02068/full