Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations

Over 250 million people are infected chronically with hepatitis B virus (HBV), the leading cause of liver cancer worldwide. HBV persists, due, in part, to its compact, stable minichromosome, the covalently-closed, circular DNA (cccDNA), which resides in the hepatocytes’ nuclei. Current the...

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Bibliographic Details
Main Authors: Vanessa Meier-Stephenson, William T. R. Bremner, Chimone S. Dalton, Guido van Marle, Carla S. Coffin, Trushar R. Patel
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/10/11/603

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