The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype

The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype

It is now appreciated that long non-coding RNAs (lncRNAs) are important players in orchestrating cancer progression. In this study we characterized GHSROS, a human lncRNA gene on the opposite DNA strand (antisense) to the ghrelin receptor gene, in prostate cancer. The lncRNA was upregulated by prost...

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Bibliographic Details
Main Authors: Patrick B. Thomas, Penny Jeffery, Manuel D. Gahete, Eliza Whiteside, Carina Walpole, Michelle Maugham, Lidija Jovanovic, Jennifer Gunter, Elizabeth Williams, Colleen Nelson, Adrian Herington, Raul M. Luque, Rakesh Veedu, Lisa K. Chopin, Inge Seim
Format: Article
Language:English
Published: PeerJ Inc. 2021-02-01
Series:PeerJ
Subjects:
Long non-coding RNA
lncRNA
Prostate cancer
Antisense transcript
Tumour growth
Gene expression
Online Access:https://peerj.com/articles/10280.pdf

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