Protein-Protein Interaction Analysis by Docking
Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms suc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2009-03-01
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Series: | Algorithms |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4893/2/1/429/ |
Summary: | Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach. |
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ISSN: | 1999-4893 |