Protein-Protein Interaction Analysis by Docking

Protein-Protein Interaction Analysis by Docking

Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms suc...

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Bibliographic Details
Main Authors: Stephan Ederer, Florian Fink, Wolfram Gronwald
Format: Article
Language:English
Published: MDPI AG 2009-03-01
Series:Algorithms
Subjects:
protein-protein docking
verification of protein interactions
3D protein structures
Online Access:http://www.mdpi.com/1999-4893/2/1/429/
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spelling doaj-e009f2c16b384f2283f79ae97b1db8f92020-11-24T21:47:09ZengMDPI AGAlgorithms1999-48932009-03-012142943610.3390/a2010429Protein-Protein Interaction Analysis by DockingStephan EdererFlorian FinkWolfram GronwaldBased on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach. http://www.mdpi.com/1999-4893/2/1/429/protein-protein dockingverification of protein interactions3D protein structures
collection DOAJ
language English
format Article
sources DOAJ
author Stephan Ederer
Florian Fink
Wolfram Gronwald
spellingShingle Stephan Ederer
Florian Fink
Wolfram Gronwald
Protein-Protein Interaction Analysis by Docking
Algorithms
protein-protein docking
verification of protein interactions
3D protein structures
author_facet Stephan Ederer
Florian Fink
Wolfram Gronwald
author_sort Stephan Ederer
title Protein-Protein Interaction Analysis by Docking
title_short Protein-Protein Interaction Analysis by Docking
title_full Protein-Protein Interaction Analysis by Docking
title_fullStr Protein-Protein Interaction Analysis by Docking
title_full_unstemmed Protein-Protein Interaction Analysis by Docking
title_sort protein-protein interaction analysis by docking
publisher MDPI AG
series Algorithms
issn 1999-4893
publishDate 2009-03-01
description Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.
topic protein-protein docking
verification of protein interactions
3D protein structures
url http://www.mdpi.com/1999-4893/2/1/429/
work_keys_str_mv AT stephanederer proteinproteininteractionanalysisbydocking
AT florianfink proteinproteininteractionanalysisbydocking
AT wolframgronwald proteinproteininteractionanalysisbydocking
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