The Role of EGFR, Hepatocyte Growth Factor Receptor (c-Met), c-ErbB2 (HER2-neu) and Clinicopathological Parameters in the Pathogenesis and Prognosis of Chordoma

The Role of EGFR, Hepatocyte Growth Factor Receptor (c-Met), c-ErbB2 (HER2-neu) and Clinicopathological Parameters in the Pathogenesis and Prognosis of Chordoma

Objective: Chordoma is a rare malignant bone tumor with a poor outcome. Although radiotherapy and gamma knife surgery have been used for treatment, providing a cure for the tumor is not easy, because of the frequent recurrences. Molecular targeted therapy against tyrosine kinases has been effective...

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Bibliographic Details
Main Authors: Zeynep TOSUNER, Türker KILIÇ, Baran YILMAZ
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2017-05-01
Series:Türk Patoloji Dergisi
Subjects:
Chordoma
EGFR
c-Met
c-Erb B2
Online Access:http://www.turkjpath.org/pdf.php3?id=1815

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