Tejaas: reverse regression increases power for detecting trans-eQTLs

Tejaas: reverse regression increases power for detecting trans-eQTLs

Abstract Trans-acting expression quantitative trait loci (trans-eQTLs) account for ≥70% expression heritability and could therefore facilitate uncovering mechanisms underlying the origination of complex diseases. Identifying trans-eQTLs is challenging because of small effect sizes, tissue specificit...

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Bibliographic Details
Main Authors:	Saikat Banerjee, Franco L. Simonetti, Kira E. Detrois, Anubhav Kaphle, Raktim Mitra, Rahul Nagial, Johannes Söding
Format:	Article
Language:	English
Published:	BMC 2021-05-01
Series:	Genome Biology
Online Access:	https://doi.org/10.1186/s13059-021-02361-8

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