Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells

Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells

A wide-range of myeloid-derived suppressor cell (MDSC)-mediated immune suppressive functions has previously been described. Nevertheless, potential novel mechanisms by which MDSCs aid tumor progression are, in all likelihood, still unrecognized. Next to its well-known expression in natural killer ce...

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Bibliographic Details
Main Authors: Inès Dufait, Julian Pardo, David Escors, Yannick De Vlaeminck, Heng Jiang, Marleen Keyaerts, Mark De Ridder, Karine Breckpot
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
MDSC
CD8+ T-cell
perforin
granzyme B
cancer
Online Access:https://www.mdpi.com/2072-6694/11/6/808

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