Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition

Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition

Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration pathway, is an important mammalian enzyme in health and disease. Its biochemical functions under physiological conditions include the metabolism of homocysteine (a cytotoxic molecule and cardiovascular risk...

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Bibliographic Details
Main Authors:	Karim Zuhra, Fiona Augsburger, Tomas Majtan, Csaba Szabo
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Biomolecules
Subjects:	hydrogen sulfide cancer Down syndrome pharmacology homocysteine cystathionine
Online Access:	https://www.mdpi.com/2218-273X/10/5/697

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