Polarized Entry of Human Parechoviruses in the Airway Epithelium

Polarized Entry of Human Parechoviruses in the Airway Epithelium

Human parechoviruses (HPeVs), a poorly studied genus within the Picornaviridae family, are classified into 19 genotypes of which HPeV1 and HPeV3 are the most often detected. HPeV1 VP1 C terminus contains an arginine-glycine-aspartic acid (RGD) motif and has been shown to depend on the host cell surf...

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Bibliographic Details
Main Authors: Eveliina Karelehto, Cosimo Cristella, Xiao Yu, Adithya Sridhar, Rens Hulsdouw, Karen de Haan, Hetty van Eijk, Sylvie Koekkoek, Dasja Pajkrt, Menno D. de Jong, Katja C. Wolthers
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
human parechovirus
airway epithelium
basal cell
host response
basolateral infection
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00294/full

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