B-1 cell-mediated modulation of M1 macrophage profile ameliorates microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi.

B-1 cell-mediated modulation of M1 macrophage profile ameliorates microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi.

Here, we have investigated the possible effect of B-1 cells on the activity of peritoneal macrophages in E. cuniculi infection. In the presence of B-1 cells, peritoneal macrophages had an M1 profile with showed increased phagocytic capacity and index, associated with the intense microbicidal activit...

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Bibliographic Details
Main Authors: Adriano Pereira, Anuska Marcelino Alvares-Saraiva, Fabiana Toshie de Camargo Konno, Diva Denelle Spadacci-Morena, Elizabeth Cristina Perez, Mario Mariano, Maria Anete Lallo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6779274?pdf=render

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