Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients
Background: For stage I–II colon cancer a significant number (5–25%) of patients has recurrent disease within 5 years. There is need to identify these high-risk patients as they might benefit from additional treatment.
Main Authors: | Wilma E. Mesker, Gerrit-Jan Liefers, Jan M. C. Junggeburt, Gabi W. van Pelt, Paola Alberici, Peter J. K. Kuppen, Noel F. Miranda, Karin A. M. van Leeuwen, Hans Morreau, Karoly Szuhai, Rob A. E. M. Tollenaar, Hans J. Tanke |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2009-01-01
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Series: | Cellular Oncology |
Online Access: | http://dx.doi.org/10.3233/CLO-2009-0478 |
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