Adiponectin Protects Against Cerebral Ischemic Injury Through AdipoR1/AMPK Pathways

Adiponectin Protects Against Cerebral Ischemic Injury Through AdipoR1/AMPK Pathways

Excitotoxicity induced by excessive N-methyl-D-aspartate (NMDA) receptor activation underlies the pathology of ischemic injury. Adiponectin (APN) is an adipocyte-derived protein hormone that modulates a number of metabolic processes. APN exerts a wide range of biological functions in the central ner...

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Bibliographic Details
Main Authors: Bin Liu, Jing Liu, Jiangong Wang, Fengjiao Sun, Shujun Jiang, Fengai Hu, Dan Wang, Dunjiang Liu, Cuilan Liu, Haijing Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
adiponectin
AdipoRon
ischemia
adiponectin receptor 1
amp-activated protein kinase
PGC-1α
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00597/full

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