Roles of Education and IQ in Cognitive Reserve in Parkinson’s Disease-Mild Cognitive Impairment

• Main Authors: M.J. Armstrong, G. Naglie, S. Duff-Canning, C. Meaney, D. Gill, P.J. Eslinger, C. Zadikoff, M. Mapstone, K.L. Chou, C. Persad, I. Litvan, B.T. Mast, S. Fox, D.F. Tang-Wai, C. Marras
• Format: Article
• Language: English
• Published: Karger Publishers 2012-08-01
• Series: Dementia and Geriatric Cognitive Disorders Extra
• Subjects: Parkinson’s disease; Mild cognitive impairment; Education; IQ; Cognitive reserve
• Online Access: http://www.karger.com/Article/FullText/341782

Background/Aims: The role of cognitive reserve in Parkinson’s disease (PD)-mild cognitive impairment (MCI) is incompletely understood. Methods: The relationships between PD-MCI, years of education, and estimated premorbid IQ were examined in 119 consecutive non-demented PD patients using logistic regression models. Results: Higher education and IQ were associated with reduced odds of PD-MCI in univariate analysis. In multivariable analysis, a higher IQ was associated with a significantly decreased odds of PD-MCI, but education was not. Conclusion: The association of higher IQ and decreased odds of PD-MCI supports a role for cognitive reserve in PD, but further studies are needed to clarify the interaction of IQ and education and the impact of other contributors such as employment and hobbies.