Forebrain NR2B overexpression facilitating the prefrontal cortex long-term potentiation and enhancing working memory function in mice.
Prefrontal cortex plays an important role in working memory, attention regulation and behavioral inhibition. Its functions are associated with NMDA receptors. However, there is little information regarding the roles of NMDA receptor NR2B subunit in prefrontal cortical synaptic plasticity and prefron...
Main Authors: | Yihui Cui, Jing Jin, Xuliang Zhang, Hao Xu, Liguo Yang, Dan Du, Qingwen Zeng, Joe Z Tsien, Huiting Yu, Xiaohua Cao |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3105019?pdf=render |
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