Single-cell RNA-seq reveals the immune escape and drug resistance mechanisms of mantle cell lymphoma

Single-cell RNA-seq reveals the immune escape and drug resistance mechanisms of mantle cell lymphoma

Objective: Mantle cell lymphoma (MCL) is a rare subtype of non-Hodgkin lymphoma (NHL) with high heterogeneity and a high recurrence rate. How heterogenous cell populations contribute to relapse remains to be elucidated. Methods: We performed single cell RNA sequencing (scRNA-seq) on approximately 4,...

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Bibliographic Details
Main Authors: Liang Wang, Steven Mo, Xin Li, Yingzhi He, Jing Yang
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-08-01
Series:Cancer Biology & Medicine
Subjects:
cell heterogeneity
immune escape
mantle cell lymphoma
multidrug resistance
scrna-seq
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1676

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