CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES
The antiphospholipid antibodies (APA) exert multiple effects on the hemostasis system causing damage to all of its protective components including the endothelial barrier, natural anticoagulant function and endogenous fibrinolysis and activating the platelet of hemostasis, which is associated with n...
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2016-06-01
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Online Access: | https://www.gynecology.su/jour/article/view/165 |
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doaj-e0c4a1d2c29145bcb4136cb0c6e1f1552021-07-28T13:44:38ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-019361010.17749/2070-4968.2015.9.3.006-010163CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURESN. S. Stuleva0D. K. Khizroeva1T. Y. Mashkova2G. R. Abramyan3First Moscow State Medical Sechenov UniversityFirst Moscow State Medical Sechenov UniversityFirst Moscow State Medical Sechenov UniversityYerevan State Medical University after Mkhitar HeratsiThe antiphospholipid antibodies (APA) exert multiple effects on the hemostasis system causing damage to all of its protective components including the endothelial barrier, natural anticoagulant function and endogenous fibrinolysis and activating the platelet of hemostasis, which is associated with numerous obstetrical complications and infertility. Objective. This study aimed at elucidating the effect of the presence of APA on the outcomes of assisted reproductive technology (ART). Materials and Methods. A total of 217 women diagnosed with infertility and planning to get pregnant using the assisted reproductive technology (ART) have been examined. Results. The results of examination demonstrated a high prevalence of circulating APA in a group of women underwent IVF failure. Conclusion. The thrombophilia can be one of the reasons of failures of in-vitro fertilization.https://www.gynecology.su/jour/article/view/165thrombophilia, ivf implantation failure, antiphospholipid antibodies, in-vitro fertilization, assisted reproductive technology, antiphospholipid syndrome |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
N. S. Stuleva D. K. Khizroeva T. Y. Mashkova G. R. Abramyan |
spellingShingle |
N. S. Stuleva D. K. Khizroeva T. Y. Mashkova G. R. Abramyan CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES Акушерство, гинекология и репродукция thrombophilia, ivf implantation failure, antiphospholipid antibodies, in-vitro fertilization, assisted reproductive technology, antiphospholipid syndrome |
author_facet |
N. S. Stuleva D. K. Khizroeva T. Y. Mashkova G. R. Abramyan |
author_sort |
N. S. Stuleva |
title |
CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES |
title_short |
CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES |
title_full |
CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES |
title_fullStr |
CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES |
title_full_unstemmed |
CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES AND IVF FAILURES |
title_sort |
circulation of antiphospholipid antibodies and ivf failures |
publisher |
IRBIS LLC |
series |
Акушерство, гинекология и репродукция |
issn |
2313-7347 2500-3194 |
publishDate |
2016-06-01 |
description |
The antiphospholipid antibodies (APA) exert multiple effects on the hemostasis system causing damage to all of its protective components including the endothelial barrier, natural anticoagulant function and endogenous fibrinolysis and activating the platelet of hemostasis, which is associated with numerous obstetrical complications and infertility. Objective. This study aimed at elucidating the effect of the presence of APA on the outcomes of assisted reproductive technology (ART). Materials and Methods. A total of 217 women diagnosed with infertility and planning to get pregnant using the assisted reproductive technology (ART) have been examined. Results. The results of examination demonstrated a high prevalence of circulating APA in a group of women underwent IVF failure. Conclusion. The thrombophilia can be one of the reasons of failures of in-vitro fertilization. |
topic |
thrombophilia, ivf implantation failure, antiphospholipid antibodies, in-vitro fertilization, assisted reproductive technology, antiphospholipid syndrome |
url |
https://www.gynecology.su/jour/article/view/165 |
work_keys_str_mv |
AT nsstuleva circulationofantiphospholipidantibodiesandivffailures AT dkkhizroeva circulationofantiphospholipidantibodiesandivffailures AT tymashkova circulationofantiphospholipidantibodiesandivffailures AT grabramyan circulationofantiphospholipidantibodiesandivffailures |
_version_ |
1721272156009005056 |