Early antiretroviral therapy during primary HIV-1 infection results in a transient reduction of the viral setpoint upon treatment interruption.

Early antiretroviral therapy during primary HIV-1 infection results in a transient reduction of the viral setpoint upon treatment interruption.

BACKGROUND: Long-term benefits of combination antiretroviral therapy (cART) initiation during primary HIV-1 infection are debated. METHODS: The evolution of plasma HIV-RNA (432 measurements) and cell-associated HIV-DNA (325 measurements) after cessation of cART (median exposure 18 months) was descri...

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Bibliographic Details
Main Authors: Viktor von Wyl, Sara Gianella, Marek Fischer, Barbara Niederoest, Herbert Kuster, Manuel Battegay, Enos Bernasconi, Matthias Cavassini, Andri Rauch, Bernard Hirschel, Pietro Vernazza, Rainer Weber, Beda Joos, Huldrych F Günthard, Swiss HIV Cohort Study-SHCS
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3216952?pdf=render

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