The Protective Effects and Mechanisms of Apelin/APJ System on Ischemic Stroke: A Promising Therapeutic Target
The orphan receptor APJ and its endogenous ligand apelin, which are expressed in the brain, are the major components of the apelin/APJ system. Growing evidence shows that the apelin/APJ system plays a vital role in the pathophysiology of cerebral ischemic injury. Targeting the apelin/APJ system may...
Main Authors: | Yanjun Tian, Ruijiao Chen, Yunlu Jiang, Bo Bai, Tongju Yang, Haiqing Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-03-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2020.00075/full |
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