Combining hydrophilic chemotherapy and hydrophobic phytotherapy via tumor-targeted albumin–QDs nano-hybrids: covalent coupling and phospholipid complexation approaches

Combining hydrophilic chemotherapy and hydrophobic phytotherapy via tumor-targeted albumin–QDs nano-hybrids: covalent coupling and phospholipid complexation approaches

Abstract Background The rationale of this study is to combine the merits of both albumin nanoparticles and quantum dots (QDs) in improved drug tumor accumulation and strong fluorescence imaging capability into one carrier. However, premature drug release from protein nanoparticles and high toxicity...

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Bibliographic Details
Main Authors: Dina G. Zayed, Shaker M. Ebrahim, Maged W. Helmy, Sherine N. Khattab, Mohammed Bahey-El-Din, Jia-You Fang, Kadria A. Elkhodairy, Ahmed O. Elzoghby
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Nanobiotechnology
Subjects:
Albumin nanoparticles
QDs
Resveratrol
Pemetrexed
Mannose targeting
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12951-019-0445-7

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