Developmental activities of the complement pathway in migrating neurons
Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.
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Nature Publishing Group
2017-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15096 |
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doaj-e11dc61947534819a52c2923baf9b3132021-05-11T07:54:12ZengNature Publishing GroupNature Communications2041-17232017-05-018111210.1038/ncomms15096Developmental activities of the complement pathway in migrating neuronsAnna Gorelik0Tamar Sapir1Rebecca Haffner-Krausz2Tsviya Olender3Trent M. Woodruff4Orly Reiner5Department of Molecular Genetics, Weizmann Institute of ScienceDepartment of Molecular Genetics, Weizmann Institute of ScienceDepartment of Veterinary Resources, Weizmann Institute of ScienceDepartment of Molecular Genetics, Weizmann Institute of ScienceSchool of Biomedical Sciences, University of Queensland, BNEDepartment of Molecular Genetics, Weizmann Institute of ScienceEmerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.https://doi.org/10.1038/ncomms15096 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner |
spellingShingle |
Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner Developmental activities of the complement pathway in migrating neurons Nature Communications |
author_facet |
Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner |
author_sort |
Anna Gorelik |
title |
Developmental activities of the complement pathway in migrating neurons |
title_short |
Developmental activities of the complement pathway in migrating neurons |
title_full |
Developmental activities of the complement pathway in migrating neurons |
title_fullStr |
Developmental activities of the complement pathway in migrating neurons |
title_full_unstemmed |
Developmental activities of the complement pathway in migrating neurons |
title_sort |
developmental activities of the complement pathway in migrating neurons |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-05-01 |
description |
Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons. |
url |
https://doi.org/10.1038/ncomms15096 |
work_keys_str_mv |
AT annagorelik developmentalactivitiesofthecomplementpathwayinmigratingneurons AT tamarsapir developmentalactivitiesofthecomplementpathwayinmigratingneurons AT rebeccahaffnerkrausz developmentalactivitiesofthecomplementpathwayinmigratingneurons AT tsviyaolender developmentalactivitiesofthecomplementpathwayinmigratingneurons AT trentmwoodruff developmentalactivitiesofthecomplementpathwayinmigratingneurons AT orlyreiner developmentalactivitiesofthecomplementpathwayinmigratingneurons |
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1721451456653950976 |