Developmental activities of the complement pathway in migrating neurons

Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.

Bibliographic Details
Main Authors:	Anna Gorelik, Tamar Sapir, Rebecca Haffner-Krausz, Tsviya Olender, Trent M. Woodruff, Orly Reiner
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms15096

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spelling	doaj-e11dc61947534819a52c2923baf9b3132021-05-11T07:54:12ZengNature Publishing GroupNature Communications2041-17232017-05-018111210.1038/ncomms15096Developmental activities of the complement pathway in migrating neuronsAnna Gorelik0Tamar Sapir1Rebecca Haffner-Krausz2Tsviya Olender3Trent M. Woodruff4Orly Reiner5Department of Molecular Genetics, Weizmann Institute of ScienceDepartment of Molecular Genetics, Weizmann Institute of ScienceDepartment of Veterinary Resources, Weizmann Institute of ScienceDepartment of Molecular Genetics, Weizmann Institute of ScienceSchool of Biomedical Sciences, University of Queensland, BNEDepartment of Molecular Genetics, Weizmann Institute of ScienceEmerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.https://doi.org/10.1038/ncomms15096
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner
spellingShingle	Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner Developmental activities of the complement pathway in migrating neurons Nature Communications
author_facet	Anna Gorelik Tamar Sapir Rebecca Haffner-Krausz Tsviya Olender Trent M. Woodruff Orly Reiner
author_sort	Anna Gorelik
title	Developmental activities of the complement pathway in migrating neurons
title_short	Developmental activities of the complement pathway in migrating neurons
title_full	Developmental activities of the complement pathway in migrating neurons
title_fullStr	Developmental activities of the complement pathway in migrating neurons
title_full_unstemmed	Developmental activities of the complement pathway in migrating neurons
title_sort	developmental activities of the complement pathway in migrating neurons
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-05-01
description	Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial migration of excitatory neurons.
url	https://doi.org/10.1038/ncomms15096
work_keys_str_mv	AT annagorelik developmentalactivitiesofthecomplementpathwayinmigratingneurons AT tamarsapir developmentalactivitiesofthecomplementpathwayinmigratingneurons AT rebeccahaffnerkrausz developmentalactivitiesofthecomplementpathwayinmigratingneurons AT tsviyaolender developmentalactivitiesofthecomplementpathwayinmigratingneurons AT trentmwoodruff developmentalactivitiesofthecomplementpathwayinmigratingneurons AT orlyreiner developmentalactivitiesofthecomplementpathwayinmigratingneurons
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Developmental activities of the complement pathway in migrating neurons

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