Comparison of Various Chromatographic Systems for Identification of Vortioxetine in Bulk Drug Substance, Human Serum, Saliva, and Urine Samples by HPLC-DAD and LC-QTOF-MS

Comparison of Various Chromatographic Systems for Identification of Vortioxetine in Bulk Drug Substance, Human Serum, Saliva, and Urine Samples by HPLC-DAD and LC-QTOF-MS

<i>Background: </i>Determination of psychotropic drugs in clinical study is significant, and the establishment of methodologies for these drugs in biological matrices is essential for patients’ safety. The search for new methods for their detection is one of the most important challenges...

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Bibliographic Details
Main Authors: Anna Petruczynik, Karol Wróblewski, Krzysztof Wojtanowski, Tomasz Mroczek, Dariusz Juchnowicz, Hanna Karakuła-Juchnowicz, Tomasz Tuzimski
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
vortioxetine
HPLC-DAD
HPLC-QTOF-MS
SPE
saliva
serum
Online Access:https://www.mdpi.com/1420-3049/25/11/2483

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