Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy

Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy

Abstract Background and aims Alcoholic fatty liver (AFL) is a liver disease caused by long-term excessive drinking and is characterized by hepatic steatosis. Understanding the regulatory mechanism of steatosis is essential for the treatment of AFL. Rev-erbα is a member of the Rev-erbs family of nucl...

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Bibliographic Details
Main Authors: Qingxue Liu, Lei Xu, Meifei Wu, Yiwen Zhou, Junfa Yang, Cheng Huang, Tao Xu, Jun Li, Lei Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell & Bioscience
Subjects:
Rev-erbα
AFL
Autophagy
Bmal1
Lysosome
Online Access:https://doi.org/10.1186/s13578-021-00622-4

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